​The BioINSouth project aims to integrate ecological considerations into regional bioeconomy strategies, focusing on circular bio-based activities. By developing guidelines and digital tools based on the SSbD assessment framework, it seeks to enhance the adoption of innovative methodologies for assessing environmental impacts in industrial bio-based systems. Targeting Southern Mediterranean European Regions, the project aims to engage stakeholders, establish regional hubs, and demonstrate its approach in partner countries, facilitating replication across other Southern European regions post-project.